- 单位：福建医科大学 附属协和医院（协和临床医学院）
- 职称：教师
- 职位：无
- 出生：197610
- 性别：女
- 社会职务：中华医学会老年医学分会青年委员 福建省医学会老年医学分会委员兼秘书 福建省医师协会老年医学科医师分会委员 中国老年学和老年医学学会老年病学分会老年高血压专家委员会委员 福建省药师协会老年药学专业委员会常务委员 中国心脏联盟心血管疾病预防与康复专业委员会福建联盟副主任委员 中华老年医学杂志、中华高血压杂志通讯编委 等
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研究领域
长期从事老年医学临床、教学和科研工作。对老年病、心血管系统疾病积累了较丰富的临床实践经验。深入开展血管衰老、高血压病等的基础研究。主持一项省自然科学基金面上项目，作为主要研究者参加三项国家卫计委科研基金项目和国自然项目，四项省自然科学基金项目。发表SCI论文6篇，国内论著9篇。作为副主编参与《老年科医生和您一起关注健康——老年人健康知识库》一书的撰写。
论文与著作
(1) Xiaoyun Shi; Siduo Zhang; Jinghui Li; Yilang Ke; Yajing Bai; Fibronectin/α5Integrin Contribute to Hypertension-Associated Arterial Ageing and Calcification through Affecting BMP2/MGP Imbalance and Enhancing Vascular Smooth Muscle Cell Phenotypic Transformation, Gerontology, DOI:10.1159/000539399 第一作者
(2) Xiaoyun Shi; Yajing Bai; Yilang Ke; Ruiqi Chen; Xiaohong Lin; Lianglong Chen; Huashan Hong; Ageing-related aorta remodelling and calcification occur earlier and progress more severely in rats with spontaneous hypertension, Histology and histopathology, 2018, 33(7): 727-736 第一作者
(3) Yajing Bai; Xiaoyun Shi; Yilang Ke; Xiaohong Lin; Huashan Hong ; Hypertension accelerates age-related intrarenal small artery (IRSA) remodelling and stiffness in rats with possible involvement of AGEs and RAGE, Histology and histopathology, 2020, 35(1): 97-109
(4) Yilang Ke; Dang Li; Mingming Zhao; Changjie Liu; Jia Liu; Aiping Zeng;
Xiaoyun Shi; Si Cheng; Bing Pan; Lemin Zheng; Huashan Hong ; Gut flora-dependent metabolite Trimethylamine-N oxide accelerates endothelial cell senescence and vascular aging through oxidative stress, Free Radical Biology and Medicine, 2018, 116: 88-100
(5) Dang Li; Yilang Ke; Rui Zhan; Changjie Liu; Mingming Zhao; Aiping Zeng;
Xiaoyun Shi; Liang Ji; Si Cheng; Bing Pan; Lemin Zheng; Huashan Hong ; Trimethylamine-N-oxide promotes brain aging and cognitive impairment in mice, Aging Cell, 2018, 17(4): e12768
Guangrong Zou; Huashan Hong; Xiaohong Lin;Xiaoyun Shi; Ying Wu; Lianglong Chen ; TRPC1,CaN and NFATC3 signaling pathway in the pathogenesis and progression of left ventricular hypertrophy in spontaneously hypertensive rats, Clin Exp Hypertens, 2014, 37(3): 223-234